名称：抗RAB7B抗体(anti- RAB7B antibody)

　　货号：FNab07044

　　适应种属：人源，小鼠

　　规格：100ug(微克)

　　状态：液体

　　纯化方法：免疫亲和纯化

　　纯度：经sds-page分析,纯度大于95

　　宿主：兔

　　亚型：igg

　　存储：用添加了0.02叠氮化钠和50甘油的pbs溶解,ph值7.3,可在-20℃下保存12个月（避免反复冻融）

　　免疫原：RAB7B, member RAS oncogene family

　　免疫原别称：Ras-related protein Rab-7b, RAB7B

　　分子量：23 kDa

　　验证应用：ELISA, WB

　　建议稀释比例：WB: 1:500-1:2000

　　克隆性：多克隆

　　uniprot id：Q96AH8

　　背景介绍：Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway。

　　图像：

　　Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab07044(RAB7B Antibody) at dilution of 1:50。

　　human heart tissue were subjected to SDS PAGE followed by western blot with FNab07044(RAB7B antibody) at dilution of 1:200。